Author(s): Jorge Alejandro Bilbao OMS, Cara L Fisher PhDLipomas are the most common type of soft-tissue tumors. Superficial lipomas account for about 50% of all soft-tissue tumors and are usually found in the upper back, neck, proximal extremities, and abdomen. Deep-seated lipomas are far less common and usually found in the lower extremity, trunk, shoulder, and upper extremity. In our study we report a case of a deep-seated, intermuscular lipoma with a rare location in the erector spinae musculature of the lower back. This mass was found during a routine dissection of a 68-year-old male cadaver and it serves to expand knowledge on the anatomical aspects of rare intermuscular lipoma locations. On gross examination, the lipomatous mass was seemingly circumscribed with a uniform, yellowish adipose color, lobulated surface, and soft consistency. Histological examination exhibited a discrete mass of uniform, mature adipocytes, which are clearly delineated from the surrounding musculature.