Autism Spectrum Disorder Symptoms Improve with Combination Therapy Directed at Improving Gut Microbiota and Reducing Inflammation
Author(s): Patrick Nemechek, Kathryn Moore
Objective: To reverse autism spectrum disorders (ASDs) by normalizing the gut microbiome and reducing pro-inflammatory cytokine
Methods: Current evidence ties autism to high levels of brain inflammation and propionic acid produced by gut bacteria. In an effort to
improve gut microflora and reduce inflammatory cytokines, patients consumed a combination of dietary supplements or antibiotics to correct
small intestine bacterial overgrowth and consumed omega-3 (fish oil) and omega-9 (olive oil) to counter inflammatory dietary omega-6 fatty
acids. Observations were made based on clinical follow-up and parent reports.
Results: Patient outcomes were dramatic and unprecedented. Within days of initiating this protocol, young children became more aware
of their surroundings, making more eye contact and initiating social interactions. Many children began speaking within 2-8 weeks and
improvement in all developmental areas was re-initiated. Within several months, teens and young adults also demonstrated recovery and
resumed the development of social skills and language. Over 12-24 months, autistic behaviors faded, developmental deficiencies resolved,
and a variety of features of autonomic function greatly improved. Within this time frame, most children under the age of seven became
indistinguishable from their peers.
Conclusions: Recent research demonstrates a connection between ASDs and the gut microbiome, highlighting the need to more fully
understand the “gut-brain axis” and how bacteria residing in the gut influence mood, learning, attention, awareness, development, and
immune function. The observations described here are unparalleled in the treatment of autism and necessitate the attention of medical
practitioners and clinical scientists.