Photochemical Screening of Ocimum Santum Leaves and Inorganic Components and Its Effects on Diabetic Rats
Author(s): Shiv Kumar Jayant, Nalini Srivastava
Phytochemical constituents and the hypoglycemic activity of aqueous and ethanolic extracts of Ocimum sanctum was investigated in alloxan
induced diabetic rats. Qualitative phytochemical screening of the methanol extracts and paroximate composition, energy, carbohydrates,
mineral elements confirmed the presence of leave extract element. Methanol extracts of Ocimum sanctum administered orally at a dose
level of 2.5 mg/kg body weight for two weeks showed a significant decrease (p<0.05) in the blood glucose and lipid profile levels of the
alloxan induced treated rats when compared with non-treated rats. Methanol extract showed a better hypoglycemic activity and antidiabetic
potentials of Ocimum sanctum extracts. Thus, its extract can be further processed for drug development.