Frontiers in Dermatology and Cosmetology


Peeling With 25% Trichloroacetic Acid Associated With Jessner’s Solution for Facial Skin Rejuvenation

Author(s): Israel Alfonso Trujillo* Idaisy Guerra Estévez, Astrid Alejandra López Cortés, Yetter Cruz León, Tamara Emilse Guerra Guerra Angela Rosa Gutiérrez Rojas

Introduction: The exfoliation with trichloroacetic acid (TCA) associated with Jessner’s solution (JS) is a procedure developed by Monheit to produce a medium depth chemical peel for the treatment of photoaged skin, actinic keratosis, melisma and superficial acne scars; however, few studies objectively evaluate its efficacy.
Objective: To evaluate the efficacy and safety of the 25% trichloroacetic acid peel associated with Jessner’s solution in the treatment of facial skin rejuvenation.
Method: An observational, analytical and longitudinal study was carried out in 200 patients from two hospitals (Surgical Clinic: “Hermanos Ameijeiras” and General Teaching: “Enrique Cabrera”), in the period between January 2010 and January 2020. Treatment it was applied monthly for 6 months. The final evaluation was carried out 3 months after the end of the treatment.
Results: 148 women and 52 men were treated with an average age of 34.3 (± 3.2) years. After treatment, there were significant changes in the Glogau Photo Damage Scale (P = 0.003), in the Lemperle Wrinkle Assessment Scale (P = 0.017) and in the Global Aesthetic Improvement Scale (P = 0.044). The adverse events found were burning, inflammation and scaling. The degree of satisfaction reported by the patients was good (1.0%) and very good (99.0%) (P = 0.001).
Conclusions: The 25% trichloroacetic acid peel associated with Jessner’s solution proved to be effective and safe to reduce the signs of facial skin aging, associated with a high degree of patient satisfaction.

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